KEGG   NETWORK: N00309
Entry
N00309                      Network                                
Name
Cortisone reduction
Definition
Cortisone+NADPH -- HSD11B1 -> Cortisol+NADP+
  Expanded
C00762+C00005 -- 3290 -> C00735+C00006
Class
nt06019 Steroid hormone biosynthesis
Type
Reference
Pathway
hsa00140  Steroid hormone biosynthesis
Gene
3290  HSD11B1; hydroxysteroid 11-beta dehydrogenase 1
Metabolite
C00762  Cortisone
C00005  NADPH
C00735  Cortisol
C00006  NADP+
Reference
  Authors
White PC, Rogoff D, McMillan DR
  Title
Physiological roles of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase.
  Journal
Curr Opin Pediatr 20:453-7 (2008)
DOI:10.1097/MOP.0b013e328305e439
Reference
  Authors
Tomlinson JW, Stewart PM
  Title
Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase.
  Journal
Best Pract Res Clin Endocrinol Metab 15:61-78 (2001)
DOI:10.1053/beem.2000.0119
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