NETWORK: N00353
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Entry
N00353 Network
Name
HPV E6 to PTEN-PIP3-AKT signaling pathway
Definition
E6 -| SLC9A3R1 -> PTEN
Expanded
K21807 -| 9368 -> 5728
Class
nt06166
Human papillomavirus (HPV)
Type
Pathogen
Pathway
hsa05165
Human papillomavirus infection
Disease
H00030
Cervical cancer
Gene
9368
SLC9A3R1; SLC9A3 regulator 1
5728
PTEN; phosphatase and tensin homolog
Perturbant
K21807
(E6)
E6; HPV protein E6
Reference
PMID:
26797638
Authors
James CD, Roberts S
Title
Viral Interactions with PDZ Domain-Containing Proteins-An Oncogenic Trait?
Journal
Pathogens 5:E8 (2016)
DOI:
10.3390/pathogens5010008
Reference
PMID:
21680517
Authors
Accardi R, Rubino R, Scalise M, Gheit T, Shahzad N, Thomas M, Banks L, Indiveri C, Sylla BS, Cardone RA, Reshkin SJ, Tommasino M
Title
E6 and E7 from human papillomavirus type 16 cooperate to target the PDZ protein Na/H exchange regulatory factor 1.
Journal
J Virol 85:8208-16 (2011)
DOI:
10.1128/JVI.00114-11
Reference
PMID:
21954943
Authors
Subbaiah VK, Kranjec C, Thomas M, Banks L
Title
PDZ domains: the building blocks regulating tumorigenesis.
Journal
Biochem J 439:195-205 (2011)
DOI:
10.1042/BJ20110903
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