| Entry |
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|---|
| Name |
HCMV gH to ITGA/B-RhoA signaling pathway
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| Definition |
UL75 -> (ITGAV+ITGB3) -> SRC -> RAC -| RHOA |
|---|
| Expanded |
K22777 -> (3685+3690) -> 6714 -> (5879,5880,5881) -| 387 |
|---|
| Class |
nt06167 Human cytomegalovirus (HCMV)
|
|---|
| Type |
Pathogen
|
|---|
| Pathway |
| hsa05163 | Human cytomegalovirus infection |
|
|---|
| Disease |
| H00368 | Cytomegalovirus infection |
|
|---|
| Gene |
| 3685 | ITGAV; integrin subunit alpha V |
| 3690 | ITGB3; integrin subunit beta 3 |
| 6714 | SRC; SRC proto-oncogene, non-receptor tyrosine kinase |
| 5879 | RAC1; Rac family small GTPase 1 |
| 5880 | RAC2; Rac family small GTPase 2 |
| 5881 | RAC3; Rac family small GTPase 3 |
| 387 | RHOA; ras homolog family member A |
|
|---|
| Perturbant |
| K22777 (UL75) | gH; Cytomegalovirus envelope glycoprotein H |
|
|---|
| Reference |
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|---|
| Authors |
Evers DL, Wang X, Huang ES |
|---|
| Title |
Cellular stress and signal transduction responses to human cytomegalovirus infection. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Wang X, Huang DY, Huong SM, Huang ES |
|---|
| Title |
Integrin alphavbeta3 is a coreceptor for human cytomegalovirus. |
|---|
| Journal |
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|---|
| LinkDB |
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