Entry
Name
HCMV pp71 to cell cycle G1/S
Definition
UL82 -> RB1 // E2F
Expanded
K22779 -> 5925 // (1869,1870,1871)
Class
nt06167 Human cytomegalovirus (HCMV)
Type
Pathogen
Pathway
hsa05163 Human cytomegalovirus infection
Disease
H00368 Cytomegalovirus infection
Gene
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
Perturbant
K22779 (UL82) UL82; Cytomegalovirus tegument protein pp71
Reference
Authors
Cinatl J Jr, Vogel JU, Kotchetkov R, Wilhelm Doerr H
Title
Oncomodulatory signals by regulatory proteins encoded by human cytomegalovirus: a novel role for viral infection in tumor progression.
Journal
Reference
Authors
Kalejta RF
Title
Human cytomegalovirus pp71: a new viral tool to probe the mechanisms of cell cycle progression and oncogenesis controlled by the retinoblastoma family of tumor suppressors.
Journal
Reference
Authors
Michaelis M, Doerr HW, Cinatl J
Title
The story of human cytomegalovirus and cancer: increasing evidence and open questions.
Journal
LinkDB
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