| Entry |
|
|---|
| Name |
HIV gp120 to CXCR4-GNAI-PI3K-BAD signaling pathway
|
|---|
| Definition |
Env -> (CXCR4,CCR5) -> GNAI |
|---|
| Expanded |
K19287 -> (7852,1234) -> (2770,2771,2773) |
|---|
| Class |
nt06533 Chemokine signaling
nt06161 Human immunodeficiency virus 1 (HIV-1)
|
|---|
| Type |
Pathogen
|
|---|
| Pathway |
| hsa05170 | Human immunodeficiency virus 1 infection |
|
|---|
| Disease |
|
|---|
| Gene |
| 7852 | CXCR4; C-X-C motif chemokine receptor 4 |
| 1234 | CCR5; C-C motif chemokine receptor 5 (gene/pseudogene) |
| 2770 | GNAI1; G protein subunit alpha i1 |
| 2771 | GNAI2; G protein subunit alpha i2 |
| 2773 | GNAI3; G protein subunit alpha i3 |
|
|---|
| Perturbant |
| K19287 (Env) | gp160; HIV-1 envelope glycoprotein gp160 |
|
|---|
| Reference |
|
|---|
| Authors |
Wu Y, Yoder A |
|---|
| Title |
Chemokine coreceptor signaling in HIV-1 infection and pathogenesis. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Choi WT, Duggineni S, Xu Y, Huang Z, An J |
|---|
| Title |
Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4). |
|---|
| Journal |
|
|---|
| LinkDB |
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|---|
