KEGG   NETWORK: N00432
Entry
N00432                      Network                                
Name
HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
Definition
Env -> (CXCR4,CCR5) -> GNAQ
  Expanded
K19287 -> (7852,1234) -> 2776
Class
nt06533 Chemokine signaling
nt06161 Human immunodeficiency virus 1 (HIV-1)
Type
Pathogen
Pathway
hsa05170  Human immunodeficiency virus 1 infection
Disease
H01563  HIV infection
Gene
7852  CXCR4; C-X-C motif chemokine receptor 4
1234  CCR5; C-C motif chemokine receptor 5 (gene/pseudogene)
2776  GNAQ; G protein subunit alpha q
Perturbant
K19287 (Env)  gp160; HIV-1 envelope glycoprotein gp160
Reference
  Authors
Wu Y, Yoder A
  Title
Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.
  Journal
PLoS Pathog 5:e1000520 (2009)
DOI:10.1371/journal.ppat.1000520
Reference
  Authors
Evans VA, Khoury G, Saleh S, Cameron PU, Lewin SR
  Title
HIV persistence: chemokines and their signalling pathways.
  Journal
Cytokine Growth Factor Rev 23:151-7 (2012)
DOI:10.1016/j.cytogfr.2012.05.002
Reference
  Authors
Abbas W, Herbein G
  Title
Plasma membrane signaling in HIV-1 infection.
  Journal
Biochim Biophys Acta 1838:1132-42 (2014)
DOI:10.1016/j.bbamem.2013.06.020
LinkDB

DBGET integrated database retrieval system