NETWORK: N00468
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Entry
N00468 Network
Name
EBV BPLF1 to TLR2/4-NFKB signaling pathway
Definition
BPLF1 -| NFKBIA
Expanded
K22972 -| 4792
Class
nt06165
Epstein-Barr virus (EBV)
Type
Pathogen
Pathway
hsa05169
Epstein-Barr virus infection
Disease
H00008
Burkitt lymphoma
H00007
Hodgkin lymphoma
H00054
Nasopharyngeal cancer
Gene
4792
NFKBIA; NFKB inhibitor alpha
Perturbant
K22972
(BPLF1)
BPLF1; EBV large tegment protein deneddylase
Reference
PMID:
24586164
Authors
van Gent M, Braem SG, de Jong A, Delagic N, Peeters JG, Boer IG, Moynagh PN, Kremmer E, Wiertz EJ, Ovaa H, Griffin BD, Ressing ME
Title
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling.
Journal
PLoS Pathog 10:e1003960 (2014)
DOI:
10.1371/journal.ppat.1003960
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