Entry |
|
Name |
CD40-NFKB signaling pathway
|
Definition |
CD40LG -> CD40 -> (TRAF2+TRAF3) -> NIK -> IKKA -> (NFKB2+RELB) |
Expanded |
959 -> 958 -> (7186+7187) -> 9020 -> 1147 -> (4791+5971) |
Class |
|
Type |
Reference
|
Pathway |
|
Gene |
7186 | TRAF2; TNF receptor associated factor 2 |
7187 | TRAF3; TNF receptor associated factor 3 |
9020 | MAP3K14; mitogen-activated protein kinase kinase kinase 14 |
1147 | CHUK; conserved helix-loop-helix ubiquitous kinase |
4791 | NFKB2; nuclear factor kappa B subunit 2 |
5971 | RELB; RELB proto-oncogene, NF-kB subunit |
|
Reference |
|
Authors |
Hayden MS, Ghosh S |
Title |
Regulation of NF-kappaB by TNF family cytokines. |
Journal |
|
Reference |
|
Authors |
Hobeika E, Nielsen PJ, Medgyesi D |
Title |
Signaling mechanisms regulating B-lymphocyte activation and tolerance. |
Journal |
|
Reference |
|
Authors |
Elgueta R, Benson MJ, de Vries VC, Wasiuk A, Guo Y, Noelle RJ |
Title |
Molecular mechanism and function of CD40/CD40L engagement in the immune system. |
Journal |
|
Reference |
|
Authors |
Bonizzi G, Karin M |
Title |
The two NF-kappaB activation pathways and their role in innate and adaptive immunity. |
Journal |
|
LinkDB |
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