Entry
Name
HTLV-1 Tax to E47-mediated transcription
Definition
TAX -| E47 => (POLB,LCK,BAX,CDKN2C)
Expanded
K21857 -| 6929 => (5423,3932,581,1031)
Class
nt06160 Human T-cell leukemia virus 1 (HTLV-1)
Type
Pathogen
Pathway
hsa05166 Human T-cell leukemia virus 1 infection
Disease
Gene
6929 TCF3; transcription factor 3
5423 POLB; DNA polymerase beta
3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
581 BAX; BCL2 associated X, apoptosis regulator
1031 CDKN2C; cyclin dependent kinase inhibitor 2C
Perturbant
K21857 (TAX) tax; HTLV protein Tax-1
Reference
Authors
Yoshida M
Title
Multiple viral strategies of HTLV-1 for dysregulation of cell growth control.
Journal
Reference
Authors
Suzuki T, Uchida-Toita M, Yoshida M
Title
Tax protein of HTLV-1 inhibits CBP/p300-mediated transcription by interfering with recruitment of CBP/p300 onto DNA element of E-box or p53 binding site.
Journal
LinkDB
All DBs