Entry |
|
Name |
HBV HBx to TGF-beta signaling pathway
|
Definition |
X -> TGFB -> (TGFBR2+TGFBR1) -> (SMAD2,SMAD3) == SMAD4 |
Expanded |
K21854 -> (7040,7042,7043) -> (7048+7046) -> (4087,4088) == 4089 |
Class |
|
Type |
Pathogen
|
Pathway |
|
Disease |
H00048 | Hepatocellular carcinoma |
|
Gene |
7040 | TGFB1; transforming growth factor beta 1 |
7042 | TGFB2; transforming growth factor beta 2 |
7043 | TGFB3; transforming growth factor beta 3 |
7048 | TGFBR2; transforming growth factor beta receptor 2 |
7046 | TGFBR1; transforming growth factor beta receptor 1 |
4087 | SMAD2; SMAD family member 2 |
4088 | SMAD3; SMAD family member 3 |
4089 | SMAD4; SMAD family member 4 |
|
Perturbant |
|
Reference |
|
Authors |
Yoo YD, Ueda H, Park K, Flanders KC, Lee YI, Jay G, Kim SJ |
Title |
Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis. |
Journal |
|
Reference |
|
Authors |
Feitelson MA, Reis HM, Tufan NL, Sun B, Pan J, Lian Z |
Title |
Putative roles of hepatitis B x antigen in the pathogenesis of chronic liver disease. |
Journal |
|
LinkDB |
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