KEGG   NETWORK: N00541
Entry
N00541                      Network                                
Name
HBV HBx to RAS-ERK signaling pathway
Definition
X -> RAS
  Expanded
K21854 -> (3265,3845,4893)
Class
nt06263 Hepatocellular carcinoma
nt06162 Hepatitis B virus (HBV)
Type
Pathogen
Pathway
hsa05161  Hepatitis B
Disease
H00048  Hepatocellular carcinoma
Gene
3265  HRAS; HRas proto-oncogene, GTPase
3845  KRAS; KRAS proto-oncogene, GTPase
4893  NRAS; NRAS proto-oncogene, GTPase
Perturbant
K21854 (X)  X; HBV protein X
Reference
  Authors
Panteva M, Korkaya H, Jameel S
  Title
Hepatitis viruses and the MAPK pathway: is this a survival strategy?
  Journal
Virus Res 92:131-40 (2003)
DOI:10.1016/S0168-1702(02)00356-8
Reference
PMID:7937954
  Authors
Benn J, Schneider RJ
  Title
Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade.
  Journal
Proc Natl Acad Sci U S A 91:10350-4 (1994)
DOI:10.1073/pnas.91.22.10350
LinkDB

DBGET integrated database retrieval system