Entry |
|
Name |
Non-canonical inflammasome signaling pathway
|
Definition |
LPS -> CASP4/5 -> (NLRP3+PYCARD+CASP1) -> (IL1B,IL18) |
Expanded |
C00338 -> (837,838) -> (114548+29108+834) -> (3553,3606) |
Class |
|
Type |
Reference
|
Pathway |
hsa04621 | NOD-like receptor signaling pathway |
|
Gene |
114548 | NLRP3; NLR family pyrin domain containing 3 |
29108 | PYCARD; PYD and CARD domain containing |
3553 | IL1B; interleukin 1 beta |
3606 | IL18; interleukin 18 |
|
Metabolite |
|
Reference |
|
Authors |
Yi YS |
Title |
Regulatory Roles of the Caspase-11 Non-Canonical Inflammasome in Inflammatory Diseases. |
Journal |
|
Reference |
|
Authors |
Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P, Hu L, Shao F |
Title |
Inflammatory caspases are innate immune receptors for intracellular LPS. |
Journal |
|
LinkDB |
|