Entry |
|
Name |
Escherichia NleH to intrinsic apoptotic pathway
|
Definition |
NleH -> TMBIM6 -| BAX |
Expanded |
K16042 -> 7009 -| 581 |
Class |
|
Type |
Pathogen
|
Pathway |
hsa05130 | Pathogenic Escherichia coli infection |
|
Disease |
H00277 | Enterohemorrhagic Escherichia coli (EHEC) infection |
H00278 | Enteropathogenic Escherichia coli (EPEC) infection |
|
Gene |
7009 | TMBIM6; transmembrane BAX inhibitor motif containing 6 |
581 | BAX; BCL2 associated X, apoptosis regulator |
|
Perturbant |
K16042 (NleH) | nleH; non-LEE-encoded effector NleH |
|
Reference |
|
Authors |
Hemrajani C, Berger CN, Robinson KS, Marches O, Mousnier A, Frankel G |
Title |
NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection. |
Journal |
|
Reference |
|
Authors |
Ashida H, Mimuro H, Ogawa M, Kobayashi T, Sanada T, Kim M, Sasakawa C |
Title |
Cell death and infection: a double-edged sword for host and pathogen survival. |
Journal |
|
LinkDB |
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