 | | NETWORK: N01202 | |
| Entry |
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| Name |
Oligomeric conformation PrPc to anterograde axonal transport
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| Definition |
PRNP* -> (GSK3B,CK2) -| (KIF5+KLC) |
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| Expanded |
5621v2 -> (2932,1457,1459,1460,283106) -| ((3798,3799,3800)+(3831,64837,147700,89953)) |
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| Class |
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| Type |
Variant
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| Pathway |
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| Disease |
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| Gene |
| 2932 | GSK3B; glycogen synthase kinase 3 beta |
| 1457 | CSNK2A1; casein kinase 2 alpha 1 |
| 1459 | CSNK2A2; casein kinase 2 alpha 2 |
| 1460 | CSNK2B; casein kinase 2 beta |
| 283106 | CSNK2A3; casein kinase 2 alpha 3 |
| 3798 | KIF5A; kinesin family member 5A |
| 3799 | KIF5B; kinesin family member 5B |
| 3800 | KIF5C; kinesin family member 5C |
| 3831 | KLC1; kinesin light chain 1 |
| 64837 | KLC2; kinesin light chain 2 |
| 147700 | KLC3; kinesin light chain 3 |
| 89953 | KLC4; kinesin light chain 4 |
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| Variant |
5621v2 (PRNP*) PRNP oligomeric conformation
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| Reference |
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| Authors |
Zamponi E, Pigino GF |
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| Title |
Protein Misfolding, Signaling Abnormalities and Altered Fast Axonal Transport: Implications for Alzheimer and Prion Diseases. |
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| Journal |
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| Reference |
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| Authors |
Zamponi E, Buratti F, Cataldi G, Caicedo HH, Song Y, Jungbauer LM, LaDu MJ, Bisbal M, Lorenzo A, Ma J, Helguera PR, Morfini GA, Brady ST, Pigino GF |
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| Title |
Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2. |
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| Journal |
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| LinkDB |
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