NETWORK: N01301
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Entry
N01301 Network
Name
Salmonella SifA to Tethering of late endosomes and lysosomes
Definition
SifA == PLEKHM1 == RAB7 == HOPS
Expanded
K15347 == 9842 == (7879,
338382) == (23339+27072+55823+57617+64601+65082)
Class
nt06181
Salmonella
Type
Pathogen
Pathway
hsa05132
Salmonella infection
Disease
H00113
Salmonellosis
Gene
9842
PLEKHM1; pleckstrin homology and RUN domain containing M1
7879
RAB7A; RAB7A, member RAS oncogene family
338382
RAB7B; RAB7B, member RAS oncogene family
23339
VPS39; VPS39 subunit of HOPS complex
27072
VPS41; VPS41 subunit of HOPS complex
55823
VPS11; VPS11 core subunit of CORVET and HOPS complexes
57617
VPS18; VPS18 core subunit of CORVET and HOPS complexes
64601
VPS16; VPS16 core subunit of CORVET and HOPS complexes
65082
VPS33A; VPS33A core subunit of CORVET and HOPS complexes
Perturbant
K15347
(SifA)
sifA; secreted effector protein SifA
Reference
PMID:
25500191
Authors
McEwan DG, Richter B, Claudi B, Wigge C, Wild P, Farhan H, McGourty K, Coxon FP, Franz-Wachtel M, Perdu B, Akutsu M, Habermann A, Kirchof A, Helfrich MH, Odgren PR, Van Hul W, Frangakis AS, Rajalingam K, Macek B, Holden DW, Bumann D, Dikic I
Title
PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.
Journal
Cell Host Microbe 17:58-71 (2015)
DOI:
10.1016/j.chom.2014.11.011
Reference
PMID:
25905573
Authors
McEwan DG, Dikic I
Title
PLEKHM1: Adapting to life at the lysosome.
Journal
Autophagy 11:720-2 (2015)
DOI:
10.1080/15548627.2015.1034419
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