Entry |
|
Name |
Salmonella SopB to Early endosomal fusion
|
Definition |
SopB -> RAB5 -> PIK3C3 -> PI3P |
Expanded |
K13085 -> (5868,5869,5878) -> 5289 -> C04549 |
Class |
|
Type |
Pathogen
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Pathway |
|
Disease |
|
Gene |
5868 | RAB5A; RAB5A, member RAS oncogene family |
5869 | RAB5B; RAB5B, member RAS oncogene family |
5878 | RAB5C; RAB5C, member RAS oncogene family |
5289 | PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 |
|
Perturbant |
K13085 (SopB) | ipgD; phosphatidylinositol-4,5-bisphosphate 4-phosphatase |
|
Metabolite |
C04549 | 1-Phosphatidyl-1D-myo-inositol 3-phosphate |
|
Reference |
|
Authors |
Mallo GV, Espina M, Smith AC, Terebiznik MR, Aleman A, Finlay BB, Rameh LE, Grinstein S, Brumell JH |
Title |
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. |
Journal |
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LinkDB |
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