Entry |
|
Name |
SARS-CoV-2 S to classical pathway of complement cascade
|
Definition |
S -> (IgG,IgM) -> ((C1QA,C1QB,C1QC)+C1R+C1S)) |
Expanded |
K24152 -> 102723407 -> ((712,713,714)+715+716)) |
Class |
|
Type |
Pathogen
|
Pathway |
|
Disease |
|
Gene |
102723407 | IGH; immunoglobulin heavy variable 4-38-2-like |
712 | C1QA; complement C1q A chain |
713 | C1QB; complement C1q B chain |
714 | C1QC; complement C1q C chain |
|
Perturbant |
K24152 (S) | S; SARS coronavirus spike glycoprotein |
|
Reference |
|
Authors |
Noris M, Benigni A, Remuzzi G |
Title |
The case of complement activation in COVID-19 multiorgan impact. |
Journal |
|
Reference |
|
Authors |
Jodele S, Kohl J |
Title |
Tackling COVID-19 infection through complement-targeted immunotherapy. |
Journal |
|
Reference |
|
Authors |
Chauhan AJ, Wiffen LJ, Brown TP |
Title |
COVID-19: A collision of complement, coagulation and inflammatory pathways. |
Journal |
|
LinkDB |
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