KEGG   NETWORK: N01441
Entry
N01441                      Network                                
Name
Wnt signaling modulation, SOST/LRP4
Definition
(SOST+LRP4) -| (FZD+LRP5/6)
  Expanded
(50964+4038) -| ((8321,2535,7976,8322,7855,8323,8324,8325,8326,11211)+(4041,4040))
Class
nt06505 WNT signaling
Type
Reference
Pathway
hsa04310  Wnt signaling pathway
Gene
50964  SOST; sclerostin
4038  LRP4; LDL receptor related protein 4
8321  FZD1; frizzled class receptor 1
2535  FZD2; frizzled class receptor 2
7976  FZD3; frizzled class receptor 3
8322  FZD4; frizzled class receptor 4
7855  FZD5; frizzled class receptor 5
8323  FZD6; frizzled class receptor 6
8324  FZD7; frizzled class receptor 7
8325  FZD8; frizzled class receptor 8
8326  FZD9; frizzled class receptor 9
11211  FZD10; frizzled class receptor 10
4041  LRP5; LDL receptor related protein 5
4040  LRP6; LDL receptor related protein 6
Reference
  Authors
Rossi M, Battafarano G, De Martino V, Scillitani A, Minisola S, Del Fattore A
  Title
Looking for new anabolic treatment from rare diseases of bone formation.
  Journal
J Endocrinol 248:R29-R40 (2021)
DOI:10.1530/JOE-20-0285
Reference
  Authors
Vasiliadis ES, Evangelopoulos DS, Kaspiris A, Benetos IS, Vlachos C, Pneumaticos SG
  Title
The Role of Sclerostin in Bone Diseases.
  Journal
J Clin Med 11:806 (2022)
DOI:10.3390/jcm11030806
Reference
  Authors
Huybrechts Y, Mortier G, Boudin E, Van Hul W
  Title
WNT Signaling and Bone: Lessons From Skeletal Dysplasias and Disorders.
  Journal
Front Endocrinol (Lausanne) 11:165 (2020)
DOI:10.3389/fendo.2020.00165
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