| Entry |
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| Name |
Classical pathway of complement cascade, C4/C2 to C3 convertase formation
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| Definition |
[C4,C2] -- ((C1QA,C1QB,C1QC)+C1R+C1S) -> [C4b,C2a] -> (C4b+C2a) |
|---|
| Expanded |
[(720,721),717] -- ((712,713,714)+715+716) -> [C22542,C22531] -> (C22542+C22531) |
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| Class |
nt06513 Complement cascade
nt06171 SARS coronavirus 2 (SARS-CoV-2)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
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| Type |
Reference
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| Pathway |
| hsa04610 | Complement and coagulation cascades |
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|---|
| Gene |
| 720 | C4A; complement C4A (Rodgers blood group) |
| 721 | C4B; complement C4B (Chido blood group) |
| 712 | C1QA; complement C1q A chain |
| 713 | C1QB; complement C1q B chain |
| 714 | C1QC; complement C1q C chain |
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| Metabolite |
| C22542 | Complement component 4b |
| C22531 | Complement component 2a |
|
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| Reference |
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| Authors |
Merle NS, Church SE, Fremeaux-Bacchi V, Roumenina LT |
|---|
| Title |
Complement System Part I - Molecular Mechanisms of Activation and Regulation. |
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| Journal |
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| LinkDB |
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