Entry |
|
Name |
Lectin pathway of coagulation cascade, fibrinogen to fibrin
|
Definition |
FG -- (F2a,((MBL2,COLEC10/11,FCN)+MASP1)) -> Fibrin |
Expanded |
(2243,2244,2266) -- (C00752,((4153,(10584,78989),(2219,2220,8547))+5648)) -> C00290 |
Class |
nt06171 SARS coronavirus 2 (SARS-CoV-2)
|
Type |
Reference
|
Gene |
2243 | FGA; fibrinogen alpha chain |
2244 | FGB; fibrinogen beta chain |
2266 | FGG; fibrinogen gamma chain |
4153 | MBL2; mannose binding lectin 2 |
10584 | COLEC10; collectin subfamily member 10 |
78989 | COLEC11; collectin subfamily member 11 |
5648 | MASP1; MBL associated serine protease 1 |
|
Metabolite |
|
Reference |
|
Authors |
Krarup A, Wallis R, Presanis JS, Gal P, Sim RB |
Title |
Simultaneous activation of complement and coagulation by MBL-associated serine protease 2. |
Journal |
|
Reference |
|
Authors |
Wiegner R, Chakraborty S, Huber-Lang M |
Title |
Complement-coagulation crosstalk on cellular and artificial surfaces. |
Journal |
|
Reference |
|
Authors |
Hess K, Ajjan R, Phoenix F, Dobo J, Gal P, Schroeder V |
Title |
Effects of MASP-1 of the complement system on activation of coagulation factors and plasma clot formation. |
Journal |
|
Reference |
|
Authors |
Gulla KC, Gupta K, Krarup A, Gal P, Schwaeble WJ, Sim RB, O'Connor CD, Hajela K |
Title |
Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot. |
Journal |
|
LinkDB |
|