KEGG   NETWORK: N01537
Entry
N01537                      Network                                
Name
Hedgehog signaling pathway, HH ligand secretion
Definition
HHAT -> HH -- DISP1 >> SCUBE2 -> HH(extracellular)
  Expanded
55733 -> (6469,3549,50846) -- 84976 >> 57758 -> (6469,3549,50846)
Class
nt06501 HH signaling
Type
Reference
Pathway
hsa04340  Hedgehog signaling pathway
Gene
55733  HHAT; hedgehog acyltransferase
6469  SHH; sonic hedgehog signaling molecule
3549  IHH; Indian hedgehog signaling molecule
50846  DHH; desert hedgehog signaling molecule
84976  DISP1; dispatched RND transporter family member 1
57758  SCUBE2; signal peptide, CUB domain and EGF like domain containing 2
Reference
  Authors
Qi X, Li X
  Title
Mechanistic Insights into the Generation and Transduction of Hedgehog Signaling.
  Journal
Trends Biochem Sci 45:397-410 (2020)
DOI:10.1016/j.tibs.2020.01.006
Reference
  Authors
Pan A, Chang L, Nguyen A, James AW
  Title
A review of hedgehog signaling in cranial bone development.
  Journal
Front Physiol 4:61 (2013)
DOI:10.3389/fphys.2013.00061
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