| | NETWORK: N01538 | |
Entry |
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Name |
Hedgehog signaling pathway, PTCH coreceptor
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Definition |
((CDON,BOC),GAS1,LRP2) -> (HH+PTCH) |
Expanded |
((50937,91653),2619,4036) -> ((6469,3549,50846)+(5727,8643)) |
Class |
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Type |
Reference
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Pathway |
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Gene |
50937 | CDON; cell adhesion associated, oncogene regulated |
91653 | BOC; BOC cell adhesion associated, oncogene regulated |
2619 | GAS1; growth arrest specific 1 |
4036 | LRP2; LDL receptor related protein 2 |
6469 | SHH; sonic hedgehog signaling molecule |
3549 | IHH; Indian hedgehog signaling molecule |
50846 | DHH; desert hedgehog signaling molecule |
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Reference |
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Authors |
Wierbowski BM, Petrov K, Aravena L, Gu G, Xu Y, Salic A |
Title |
Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand. |
Journal |
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Reference |
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Authors |
Christ A, Herzog K, Willnow TE |
Title |
LRP2, an auxiliary receptor that controls sonic hedgehog signaling in development and disease. |
Journal |
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LinkDB |
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