| Entry |
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| Name |
Regulation of GF-RTK-RAS-ERK signaling pathway, adaptor proteins
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| Definition |
(PTPN11,SHC,GAB,GRB2) -> SOS |
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| Expanded |
(5781,(6464,25759,53358,399694),(2549,9846),2885) -> (6654,6655) |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 5781 | PTPN11; protein tyrosine phosphatase non-receptor type 11 |
| 6464 | SHC1; SHC adaptor protein 1 |
| 25759 | SHC2; SHC adaptor protein 2 |
| 53358 | SHC3; SHC adaptor protein 3 |
| 399694 | SHC4; SHC adaptor protein 4 |
| 2549 | GAB1; GRB2 associated binding protein 1 |
| 9846 | GAB2; GRB2 associated binding protein 2 |
| 2885 | GRB2; growth factor receptor bound protein 2 |
| 6654 | SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1 |
| 6655 | SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2 |
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| Reference |
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| Authors |
Niogret C, Birchmeier W, Guarda G |
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| Title |
SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling. |
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| Journal |
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| Reference |
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| Authors |
Pudewell S, Ahmadian MR |
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| Title |
Spotlight on Accessory Proteins: RTK-RAS-MAPK Modulators as New Therapeutic Targets. |
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| Journal |
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| LinkDB |
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