| Entry |
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| Name |
Regulation of GF-RTK-RAS-ERK signaling, MRAS-SHOC2-PP1 holophosphatase
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| Definition |
(MRAS+SHOC2+PP1) -> RAF |
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| Expanded |
(22808+8036+(5499,5500,5501)) -> (369,673,5894) |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 22808 | MRAS; muscle RAS oncogene homolog |
| 8036 | SHOC2; SHOC2 leucine rich repeat scaffold protein |
| 5499 | PPP1CA; protein phosphatase 1 catalytic subunit alpha |
| 5500 | PPP1CB; protein phosphatase 1 catalytic subunit beta |
| 5501 | PPP1CC; protein phosphatase 1 catalytic subunit gamma |
| 369 | ARAF; A-Raf proto-oncogene, serine/threonine kinase |
| 673 | BRAF; B-Raf proto-oncogene, serine/threonine kinase |
| 5894 | RAF1; Raf-1 proto-oncogene, serine/threonine kinase |
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| Reference |
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| Authors |
Pudewell S, Wittich C, Kazemein Jasemi NS, Bazgir F, Ahmadian MR |
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| Title |
Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line. |
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| Journal |
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| Reference |
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| Authors |
Tartaglia M, Aoki Y, Gelb BD |
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| Title |
The molecular genetics of RASopathies: An update on novel disease genes and new disorders. |
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| Journal |
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| LinkDB |
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