KEGG   NETWORK: N01718
Entry
N01718                      Network                                
Name
Autophagy-vesicle nucleation/elongation/maturation, PACER-RUBCN-PI3KC3-C2
Definition
RUBCNL -| RUBCN -| PI3KC3-C2
  Expanded
80183 -| 9711 -| (8678+5289+30849+29982+7405)
Class
nt06532 Autophagy
Type
Reference
Pathway
hsa04140  Autophagy - animal
Gene
80183  RUBCNL; rubicon like autophagy enhancer
9711  RUBCN; rubicon autophagy regulator
8678  BECN1; beclin 1
5289  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
30849  PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
29982  NRBF2; nuclear receptor binding factor 2
7405  UVRAG; UV radiation resistance associated
Reference
  Authors
Zhao YG, Codogno P, Zhang H
  Title
Machinery, regulation and pathophysiological implications of autophagosome maturation.
  Journal
Nat Rev Mol Cell Biol 22:733-750 (2021)
DOI:10.1038/s41580-021-00392-4
Reference
  Authors
Gillson J, Abd El-Aziz YS, Leck LYW, Jansson PJ, Pavlakis N, Samra JS, Mittal A, Sahni S
  Title
Autophagy: A Key Player in Pancreatic Cancer Progression and a Potential Drug Target.
  Journal
Cancers (Basel) 14:cancers14143528 (2022)
DOI:10.3390/cancers14143528
Reference
  Authors
Dossou AS, Basu A
  Title
The Emerging Roles of mTORC1 in Macromanaging Autophagy.
  Journal
Cancers (Basel) 11:cancers11101422 (2019)
DOI:10.3390/cancers11101422
Reference
  Authors
Vitto VAM, Bianchin S, Zolondick AA, Pellielo G, Rimessi A, Chianese D, Yang H, Carbone M, Pinton P, Giorgi C, Patergnani S
  Title
Molecular Mechanisms of Autophagy in Cancer Development, Progression, and Therapy.
  Journal
Biomedicines 10:biomedicines10071596 (2022)
DOI:10.3390/biomedicines10071596
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