KEGG   NETWORK: N01766
Entry
N01766                      Network                                
Name
CX3CR1-GNAI-AC signaling pathway
Definition
CX3CL1 -> CX3CR1 -> GNAI -| ADCY
  Expanded
6376 -> 1524 -> (2770,2771,2773) -| (107,108,109,196883,111,112,113,114,115)
Class
nt06533 Chemokine signaling
Type
Reference
Pathway
hsa04062  Chemokine signaling pathway
Gene
6376  CX3CL1; C-X3-C motif chemokine ligand 1
1524  CX3CR1; C-X3-C motif chemokine receptor 1
2770  GNAI1; G protein subunit alpha i1
2771  GNAI2; G protein subunit alpha i2
2773  GNAI3; G protein subunit alpha i3
107  ADCY1; adenylate cyclase 1
108  ADCY2; adenylate cyclase 2
109  ADCY3; adenylate cyclase 3
196883  ADCY4; adenylate cyclase 4
111  ADCY5; adenylate cyclase 5
112  ADCY6; adenylate cyclase 6
113  ADCY7; adenylate cyclase 7
114  ADCY8; adenylate cyclase 8
115  ADCY9; adenylate cyclase 9
Reference
  Authors
Lee M, Lee Y, Song J, Lee J, Chang SY
  Title
Tissue-specific Role of CX3CR1 Expressing Immune Cells and Their Relationships with Human Disease.
  Journal
Immune Netw 18:e5 (2018)
DOI:10.4110/in.2018.18.e5
Reference
  Authors
Oh DY, Olefsky JM
  Title
G protein-coupled receptors as targets for anti-diabetic therapeutics.
  Journal
Nat Rev Drug Discov 15:161-72 (2016)
DOI:10.1038/nrd.2015.4
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