KEGG   NETWORK: N01783
Entry
N01783                      Network                                
Name
NPPA-NPR1 signaling
Definition
NPPA -> NPR1 -> cGMP -> PRKG1/2
  Expanded
4878 -> 4881 -> C00942 -> 5592,5593
Class
nt06325 Hormone/cytokine signaling
Type
Reference
Gene
4878  NPPA; natriuretic peptide A
4881  NPR1; natriuretic peptide receptor 1
5592  PRKG1; protein kinase cGMP-dependent 1
5593  PRKG2; protein kinase cGMP-dependent 2
Metabolite
C00942  3',5'-Cyclic GMP
Reference
PMID:24820868
  Authors
Zois NE, Bartels ED, Hunter I, Kousholt BS, Olsen LH, Goetze JP
  Title
Natriuretic peptides in cardiometabolic regulation and disease.
  Journal
Nat Rev Cardiol 11:403-12 (2014)
DOI:10.1038/nrcardio.2014.64
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