KEGG   NETWORK: N01792
Entry
N01792                      Network                                
Name
EDN-EDNR signaling pathway
Definition
EDN1/2/3 -> EDNRA/B -> GNAQ,GNA11
  Expanded
1906,1907,1908 -> 1909,1910 -> 2776,2767
Class
nt06325 Hormone/cytokine signaling
Type
Reference
Gene
1906  EDN1; endothelin 1
1907  EDN2; endothelin 2
1908  EDN3; endothelin 3
1909  EDNRA; endothelin receptor type A
1910  EDNRB; endothelin receptor type B
2776  GNAQ; G protein subunit alpha q
2767  GNA11; G protein subunit alpha 11
Reference
PMID:30171849
  Authors
Bondurand N, Dufour S, Pingault V
  Title
News from the endothelin-3/EDNRB signaling pathway: Role during enteric nervous system development and involvement in neural crest-associated disorders.
  Journal
Dev Biol 444 Suppl 1:S156-S169 (2018)
DOI:10.1016/j.ydbio.2018.08.014
Reference
PMID:23884378
  Authors
Rosano L, Spinella F, Bagnato A
  Title
Endothelin 1 in cancer: biological implications and therapeutic opportunities.
  Journal
Nat Rev Cancer 13:637-51 (2013)
DOI:10.1038/nrc3546
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