KEGG   DRUG: クロルタリドン
エントリ  
D00272                      Drug                                   
一般名   
クロルタリドン (JAN);
Chlorthalidone (USP);
Chlortalidone (JAN/INN)
米国の商品 
  後発品
CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (Ajanta Pharma USA), CHLORTHALIDONE (Alembic Pharmaceuticals Limited), CHLORTHALIDONE (Alembic Pharmaceuticals), CHLORTHALIDONE (American Health Packaging), CHLORTHALIDONE (Amneal Pharmaceuticals LLC), CHLORTHALIDONE (Aphena Pharma Solutions - Tennessee), CHLORTHALIDONE (Aphena Pharma Solutions - Tennessee), CHLORTHALIDONE (Aphena Pharma Solutions - Tennessee), CHLORTHALIDONE (Aphena Pharma Solutions - Tennessee), CHLORTHALIDONE (Ascend Laboratories), CHLORTHALIDONE (AvPAK), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Chartwell RX), CHLORTHALIDONE (Direct_Rx), CHLORTHALIDONE (Direct_Rx), CHLORTHALIDONE (Dr. Reddy's Laboratories), CHLORTHALIDONE (Dr. Reddy's Laboratories), CHLORTHALIDONE (JUBILANT CADISTA PHARMACEUTICALS), CHLORTHALIDONE (Lifestar Pharma LLC), CHLORTHALIDONE (Major Pharmaceuticals), CHLORTHALIDONE (Mylan Institutional), CHLORTHALIDONE (Mylan Pharmaceuticals), CHLORTHALIDONE (Nivagen Pharmaceuticals), CHLORTHALIDONE (Northstar Rx LLC.), CHLORTHALIDONE (Northwind Pharmaceuticals), CHLORTHALIDONE (Northwind Pharmaceuticals), CHLORTHALIDONE (Northwind Pharmaceuticals), CHLORTHALIDONE (Northwind Pharmaceuticals), CHLORTHALIDONE (Northwind Pharmaceuticals), CHLORTHALIDONE (NuCare Pharmaceuticals), CHLORTHALIDONE (PD-Rx Pharmaceuticals), CHLORTHALIDONE (PD-Rx Pharmaceuticals), CHLORTHALIDONE (Preferred Pharmaceuticals), CHLORTHALIDONE (Proficient Rx LP), CHLORTHALIDONE (REMEDYREPACK), CHLORTHALIDONE (REMEDYREPACK), CHLORTHALIDONE (REMEDYREPACK), CHLORTHALIDONE (RPK Pharmaceuticals), CHLORTHALIDONE (RPK Pharmaceuticals), CHLORTHALIDONE (Rising Pharmaceuticals), CHLORTHALIDONE (Sun Pharmaceutical Industries), CHLORTHALIDONE (TAGI Pharma), CHLORTHALIDONE (Unichem Pharmaceuticals (USA)), CHLORTHALIDONE (Zydus Lifesciences Limited), CHLORTHALIDONE (Zydus Pharmaceuticals USA)
組成式   
C14H11ClN2O4S
質量    
338.0128
分子量   
338.7661
構造式   
クラス   
心血管系用薬
 DG03231  血圧降下薬
  DG02992  チアジド類似利尿薬
 DG01690  スルホンアミド系利尿薬
  DG02992  チアジド類似利尿薬
コード   
ATCコード: C03BA04
商品: D00272<US>
商品 (mixture): D10589<US> D10592<US>
効能    
血圧降下薬, 利尿薬, Na+-Cl-再吸収阻害薬
コメント  
スルホンアミド誘導体
ターゲット 
SLC12A3 (TSC) [HSA:6559] [KO:K14426]
SLC12A1 (NKCC2) [HSA:6557] [KO:K14425]
相互作用  

構造マップ 
map07017  スルホンアミド誘導体 - 利尿剤
map07233  イオントランスポーター阻害薬
階層分類  
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C03 利尿薬
   C03B 低許容値の利尿薬、チアジドを除く
    C03BA スルホンアミド、単剤
     C03BA04 クロルタリドン
      D00272  クロルタリドン (JAN) <US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  チアジド系利尿薬
   クロルタリドン
    D00272  クロルタリドン (JAN)
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG03231  血圧降下薬
   DG02992  チアジド類似利尿薬
    D00272  クロルタリドン
  DG01690  スルホンアミド系利尿薬
   DG02992  チアジド類似利尿薬
    D00272  クロルタリドン
ターゲットに基づく医薬品分類 [BR:jp08310]
 トランスポーター
  SLC ファミリー
   SLC12
    SLC12A1 (NKCC2)
     D00272  クロルタリドン (JAN) <US>
    SLC12A3 (TSC)
     D00272  クロルタリドン (JAN) <US>
リンク   
CAS: 77-36-1
PubChem: 7847338
LigandBox: D00272
日化辞: J1.476A
LinkDB    

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