KEGG   DRUG: シルデナフィルクエン酸塩
エントリ  
D02229                      Drug                                   
一般名   
シルデナフィルクエン酸塩 (JAN);
Sildenafil citrate (JAN/USP)
商品名   
  後発品
米国の商品 
  後発品
SILDENAFIL (A-S Medication Solutions), SILDENAFIL (A-S Medication Solutions), SILDENAFIL (A-S Medication Solutions), SILDENAFIL (A-S Medication Solutions), SILDENAFIL (A-S Medication Solutions), SILDENAFIL (A-S Medication Solutions), SILDENAFIL (ANI Pharmaceuticals), SILDENAFIL (Actavis Pharma), SILDENAFIL (Advagen Pharma), SILDENAFIL (Ajanta Pharma USA), SILDENAFIL (Ajanta Pharma USA), SILDENAFIL (American Health Packaging), SILDENAFIL (Amneal Pharmaceuticals LLC), SILDENAFIL (Amneal Pharmaceuticals NY LLC), SILDENAFIL (Amneal Pharmaceuticals NY LLC), SILDENAFIL (Amneal Pharmaceuticals NY LLC), SILDENAFIL (Aphena Pharma Solutions - Tennessee), SILDENAFIL (Aphena Pharma Solutions - Tennessee), SILDENAFIL (Aphena Pharma Solutions - Tennessee), SILDENAFIL (Aphena Pharma Solutions - Tennessee), SILDENAFIL (Aphena Pharma Solutions - Tennessee), SILDENAFIL (Appco Pharma LLC), SILDENAFIL (Asclemed USA), SILDENAFIL (Aurobindo Pharma Limited), SILDENAFIL (Aurobindo Pharma Limited), SILDENAFIL (AustarPharma LLC), SILDENAFIL (AvKARE), SILDENAFIL (AvPAK), SILDENAFIL (BluePoint Laboratories), SILDENAFIL (Bryant Ranch Prepack), SILDENAFIL (Bryant Ranch Prepack), SILDENAFIL (Bryant Ranch Prepack), SILDENAFIL (Bryant Ranch Prepack), SILDENAFIL (Bryant Ranch Prepack), SILDENAFIL (Bryant Ranch Prepack), SILDENAFIL (Bryant Ranch Prepack), SILDENAFIL (CIPLA USA INC.,), SILDENAFIL (Cadila Pharmaceuticals Limited), SILDENAFIL (Camber Pharmaceuticals), SILDENAFIL (Camber Pharmaceuticals), SILDENAFIL (Camber Pharmaceuticals), SILDENAFIL (Camber Pharmaceuticals), SILDENAFIL (Chartwell RX), SILDENAFIL (DIRECT RX), SILDENAFIL (DIRECT RX), SILDENAFIL (DirectRx), SILDENAFIL (Eugia US LLC), SILDENAFIL (Exelan Pharmaceuticals), SILDENAFIL (Greenstone LLC), SILDENAFIL (Lake Erie Medical DBA Quality Care Products LLC), SILDENAFIL (Lupin Pharmaceuticals), SILDENAFIL (Macleods Pharmaceuticals Limited), SILDENAFIL (Macleods Pharmaceuticals Limited), SILDENAFIL (Macleods Pharmaceuticals Limited), SILDENAFIL (McKesson Corporation dba SKY Packaging), SILDENAFIL (Medsource Pharmaceuticals), SILDENAFIL (Modavar Pharmaceuticals LLC), SILDENAFIL (Mylan Pharmaceuticals), SILDENAFIL (Northwind Pharmaceuticals), SILDENAFIL (Northwind Pharmaceuticals), SILDENAFIL (Northwind Pharmaceuticals), SILDENAFIL (Northwind Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (NuCare Pharmaceuticals), SILDENAFIL (PD-Rx Pharmaceuticals), SILDENAFIL (PD-Rx Pharmaceuticals), SILDENAFIL (PD-Rx Pharmaceuticals), SILDENAFIL (PD-Rx Pharmaceuticals), SILDENAFIL (PD-Rx Pharmaceuticals), SILDENAFIL (Pharmasource Meds), SILDENAFIL (Preferred Pharmaceuticals), SILDENAFIL (Preferred Pharmaceuticals), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Proficient Rx LP), SILDENAFIL (Quallent Pharmaceuticals Health LLC), SILDENAFIL (REMEDYREPACK), SILDENAFIL (REMEDYREPACK), SILDENAFIL (REMEDYREPACK), SILDENAFIL (REMEDYREPACK), SILDENAFIL (REMEDYREPACK), SILDENAFIL (RPK Pharmaceuticals), SILDENAFIL (RPK Pharmaceuticals), SILDENAFIL (RPK Pharmaceuticals), SILDENAFIL (RPK Pharmaceuticals), SILDENAFIL (Reyoung Corporation), SILDENAFIL (Taro Pharmaceuticals U.S.A.), SILDENAFIL (Teva Pharmaceuticals USA), SILDENAFIL (Teva Pharmaceuticals USA), SILDENAFIL (Tris Pharma), SILDENAFIL (TruPharma LLC), SILDENAFIL (Virtus Pharmaceuticals), SILDENAFIL (XLCARE Pharmaceuticals), SILDENAFIL (XLCare Pharmaceuticals), SILDENAFIL CITRATE (A-S Medication Solutions), SILDENAFIL CITRATE (A-S Medication Solutions), SILDENAFIL CITRATE (ANI Pharmaceuticals), SILDENAFIL CITRATE (Advagen Pharma), SILDENAFIL CITRATE (Advanced Rx Pharmacy of Tennessee), SILDENAFIL CITRATE (Ajanta Pharma USA), SILDENAFIL CITRATE (Ascend Laboratories), SILDENAFIL CITRATE (Asclemed USA), SILDENAFIL CITRATE (Asclemed USA), SILDENAFIL CITRATE (Aurobindo Pharma Limited), SILDENAFIL CITRATE (Bryant Ranch Prepack), SILDENAFIL CITRATE (Cardinal Health 107), SILDENAFIL CITRATE (Greenstone LLC), SILDENAFIL CITRATE (Major Pharmaceuticals), SILDENAFIL CITRATE (NIVAGEN PHARMACEUTICALS), SILDENAFIL CITRATE (Northwind Pharmaceuticals), SILDENAFIL CITRATE (Northwind Pharmaceuticals), SILDENAFIL CITRATE (Novadoz Pharmaceuticals LLC), SILDENAFIL CITRATE (NuCare Pharmaceuticals), SILDENAFIL CITRATE (NuCare Pharmaceuticals), SILDENAFIL CITRATE (NuCare Pharmaceuticals), SILDENAFIL CITRATE (PD-Rx Pharmaceuticals), SILDENAFIL CITRATE (PD-Rx Pharmaceuticals), SILDENAFIL CITRATE (Preferred Pharmaceuticals), SILDENAFIL CITRATE (Proficient Rx LP), SILDENAFIL CITRATE (Proficient Rx LP), SILDENAFIL CITRATE (Proficient Rx LP), SILDENAFIL CITRATE (Proficient Rx LP), SILDENAFIL CITRATE (Proficient Rx LP), SILDENAFIL CITRATE (Proficient Rx LP), SILDENAFIL CITRATE (Proficient Rx LP), SILDENAFIL CITRATE (Quality Care Products), SILDENAFIL CITRATE (Quallent Pharmaceuticals Health LLC), SILDENAFIL CITRATE (REMEDYREPACK), SILDENAFIL CITRATE (REMEDYREPACK), SILDENAFIL CITRATE (RedPharm Drug), SILDENAFIL CITRATE (Torrent Pharmaceuticals Limited), SILDENAFIL CITRATE (Torrent Pharmaceuticals Limited), SILDENAFIL CITRATE (TruPharma LLC), SILDENAFIL CITRATE (Zydus Lifesciences Limited), SILDENAFIL CITRATE (Zydus Pharmaceuticals (USA))
組成式   
C22H30N6O4S. C6H8O7
質量    
666.2319
分子量   
666.6999
構造式   
クラス   
心血管系用薬
 DG01509  ホスホジエステラーゼV阻害薬
代謝酵素基質薬
 DG01642  CYP2C9基質薬
 DG01633  CYP3A/CYP3A4基質薬
  DG02913  CYP3A4基質薬
コード   
薬効分類: 2190 2590
ATCコード: G04BE03
化学構造グループ: DG00484
商品 (DG00484): D02229<JP/US>
効能    
血管拡張薬, 勃起不全治療薬, ホスホジエステラーゼV阻害薬
  疾患
肺動脈性肺高血圧症 [DS:H01621]
ターゲット 
PDE5 [HSA:8654] [KO:K13762]
  パスウェイ
hsa04022  cGMP-PKG シグナル伝達経路
代謝    
Enzyme: CYP3A4 [HSA:1576]; CYP2C9 [HSA:1559]
相互作用  

階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   219  その他の循環器官用薬
    2190  その他の循環器官用薬
     D02229  シルデナフィルクエン酸塩 (JAN)
  25  泌尿生殖器官及び肛門用薬
   259  その他の泌尿生殖器官及び肛門用薬
    2590  その他の泌尿生殖器官及び肛門用薬
     D02229  シルデナフィルクエン酸塩 (JAN)
医療用医薬品のATC分類 [BR:jp08303]
 G 泌尿生殖器系と性ホルモン
  G04 泌尿器科用薬
   G04B 泌尿器科用薬
    G04BE 勃起不全用薬
     G04BE03 シルデナフィル
      D02229  シルデナフィルクエン酸塩 (JAN) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 呼吸器薬
  肺血圧降下薬
   ホスホジエステラーゼ-5 (PDE5)阻害薬
    シルデナフィル
     D02229  シルデナフィルクエン酸塩 (JAN)
 性的障害治療薬
  性的障害治療薬(男性)
   シルデナフィル
    D02229  シルデナフィルクエン酸塩 (JAN)
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG01509  ホスホジエステラーゼV阻害薬
   DG00484  シルデナフィル
    D02229  シルデナフィルクエン酸塩
 代謝酵素基質薬
  DG01642  CYP2C9基質薬
   DG00484  シルデナフィル
    D02229  シルデナフィルクエン酸塩
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00484  シルデナフィル
     D02229  シルデナフィルクエン酸塩
ターゲットに基づく医薬品分類 [BR:jp08310]
 酵素
  ヒドロラーゼ (EC3)
   ホスホジエステラーゼ
    PDE5
     D02229  シルデナフィルクエン酸塩 (JAN) <JP/US>
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D02229
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG01509  ホスホジエステラーゼV阻害薬
   DG00484  シルデナフィル
 代謝酵素基質薬
  DG01642  CYP2C9基質薬
   DG00484  シルデナフィル
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00484  シルデナフィル
リンク   
CAS: 171599-83-0
PubChem: 7849288
LigandBox: D02229
日化辞: J974.104F
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