オララツマブ (遺伝子組換え) (JAN);
Olaratumab (USAN/INN);
Olaratumab (genetical recombination) (JAN)

C6554H10076N1736O2048S40

147148.6495

147239.1336

(Heavy chain)
QLQLQESGPG LVKPSETLSL TCTVSGGSIN SSSYYWGWLR QSPGKGLEWI GSFFYTGSTY
YNPSLRSRLT ISVDTSKNQF SLMLSSVTAA DTAVYYCARQ STYYYGSGNY YGWFDRWDQG
TLVTVSSAST KGPSVFPLAP SSKSTSGGTA ALGCLVKDYF PEPVTVSWNS GALTSGVHTF
PAVLQSSGLY SLSSVVTVPS SSLGTQTYIC NVNHKPSNTK VDKRVEPKSC DKTHTCPPCP
APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK
PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT
LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL
TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK
(Light chain)
EIVLTQSPAT LSLSPGERAT LSCRASQSVS SYLAWYQQKP GQAPRLLIYD ASNRATGIPA
RFSGSGSGTD FTLTISSLEP EDFAVYYCQQ RSNWPPAFGQ GTKVEIKRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(Disulfide bridge: H22-H97, H154-H210, H271-H331, H377-H435, H236-H'236, H239-H'239, L23-L88, L134-L194, H230-L214)

抗悪性腫瘍薬, 抗血小板由来成長因子(PDGF)受容体α抗体

PDGFRA [HSA:5156] [KO:K04363]

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