ミリキズマブ (遺伝子組換え) (JAN);
Mirikizumab (USAN/INN);
Mirikizumab (genetical recombination) (JAN);
Mirikizumab-mrkz

オンボー (日本イーライリリー), オンボー (日本イーライリリー)
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C6380H9842N1686O2004S48

143676.665

143765.6253

(Heavy chain)
QVQLVQSGAE VKKPGSSVKV SCKASGYKFT RYVMHWVRQA PGQGLEWMGY INPYNDGTNY
NEKFKGRVTI TADKSTSTAY MELSSLRSED TAVYYCARNW DTGLWGQGTT VTVSSASTKG
PSVFPLAPCS RSTSESTAAL GCLVKDYFPE PVTVSWNSGA LTSGVHTFPA VLQSSGLYSL
SSVVTVPSSS LGTKTYTCNV DHKPSNTKVD KRVESKYGPP CPPCPAPEAA GGPSVFLFPP
KPKDTLMISR TPEVTCVVVD VSQEDPEVQF NWYVDGVEVH NAKTKPREEQ FNSTYRVVSV
LTVLHQDWLN GKEYKCKVSN KGLPSSIEKT ISKAKGQPRE PQVYTLPPSQ EEMTKNQVSL
TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSRLTVDKS RWQEGNVFSC
SVMHEALHNH YTQKSLSLSL G
(Light chain)
DIQMTQSPSS LSASVGDRVT ITCKASDHIL KFLTWYQQKP GKAPKLLIYG ATSLETGVPS
RFSGSGSGTD FTLTISSLQP EDFATYYCQM YWSTPFTFGG GTKVEIKRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(Disulfide bridge: H22-H96, H129-L214, H142-H198, H221-H'221, H224-H'224, H256-H316, H362-H420, H'22-H'96, H'129-L'214, H'142-H'198, H'256-H'316, H'362-H'420, L23-L88, L134-L194, L'23-L'88, L'134-L'194)

抗炎症薬, 乾癬治療薬, 抗IL-23抗体

IL23A [HSA:51561] [KO:K05426]

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