KEGG   DISEASE: 脊柱管狭窄
エントリ  
H01711                                                             
名称    
脊柱管狭窄
概要    
Spinal stenosis is an abnormal narrowing of the spinal canal that mainly occurs in the cervical and lumbar regions. Cervical stenosis presents with axial neck pain, radiculopathy, myelopathy, or a combination of these presentations. Axial pain refers to pain that occurs along the spinal column, while radiculopathy refers to complaints in a dermatomal or myotomal distribution often occurring in the arms. Patients may complain of numbness, pain or loss of function. Myelopathy refers to a cluster of complaints and findings due to intrinsic damage to the spinal cord itself. Patients might report numbness, coordination and gait issues, grip weakness and bowel and bladder complaint. Lumbar spinal stenosis is a major cause of pain and functional disability for the elderly. Neurogenic claudication symptoms are a hallmark of lumbar spinal stenosis, where patients develop low back or leg pain when walking or standing that is relieved by sitting or lumbar flexion. The treatment of lumbar spinal stenosis generally begins with conservative management such as physical therapy, home exercise programs, and oral analgesics. Once these therapies fail, patients commonly move forward with interventional pain treatment options such as epidural steroid injections (ESIs), nerve block, or surgery as the next step. Coexisting lumbar and cervical stenosis (tandem spinal stenosis) is an infrequent presentation with mixed presentation of upper motor neuron and lower motor neuron signs. But very few reports of tandem spinal stenosis are available.
カテゴリ  
筋骨格疾患
階層分類  
ICD-11 による疾患分類 [BR:jp08403]
 15 筋骨格系・結合組織の疾患
  脊椎に関連する病態
   脊椎の変性病態
    FA82  脊柱管狭窄
     H01711  脊柱管狭窄
指定難病 [jp08407.html]
 H01711
治療薬   
リマプロストアルファデクス [DR:D02860]
リンク   
ICD-11: FA82
ICD-10: M48.0
MeSH: D013130
OMIM: 152550
文献    
  著者
Todd AG
  タイトル
Cervical spine: degenerative conditions.
  雑誌
Curr Rev Musculoskelet Med 4:168-74 (2011)
DOI:10.1007/s12178-011-9099-2
文献    
  著者
Benyamin RM, Staats PS, MiDAS Encore I
  タイトル
MILD(R) Is an Effective Treatment for Lumbar Spinal Stenosis with Neurogenic Claudication: MiDAS ENCORE Randomized Controlled Trial.
  雑誌
Pain Physician 19:229-42 (2016)
文献    
  著者
Krishnan A, Dave BR, Kambar AK, Ram H
  タイトル
Coexisting lumbar and cervical stenosis (tandem spinal stenosis): an infrequent presentation. Retrospective analysis of single-stage surgery (53 cases).
  雑誌
Eur Spine J 23:64-73 (2014)
DOI:10.1007/s00586-013-2868-4
文献    
  著者
Tran DQ, Duong S, Finlayson RJ
  タイトル
Lumbar spinal stenosis: a brief review of the nonsurgical management.
  雑誌
Can J Anaesth 57:694-703 (2010)
DOI:10.1007/s12630-010-9315-3
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