KEGG   VARIANT: 4297v1
Entry
4297v1                      Variant                                
Name
MLL-AF4 fusion
Gene
KMT2A  lysine methyltransferase 2A [KO:K09186]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
translocation t(4;11)
COSF: 1947 2067 1949
Network
nt06240  Transcription (cancer)
Disease
H00001  B-cell acute lymphoblastic leukemia
Reference
PMID:19141473
  Authors
Guenther MG, Lawton LN, Rozovskaia T, Frampton GM, Levine SS, Volkert TL, Croce CM, Nakamura T, Canaani E, Young RA
  Title
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
  Journal
Genes Dev 22:3403-8 (2008)
DOI:10.1101/gad.1741408
Reference
PMID:19535349
  Authors
Slany RK
  Title
The molecular biology of mixed lineage leukemia.
  Journal
Haematologica 94:984-93 (2009)
DOI:10.3324/haematol.2008.002436
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