| Entry |
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| Name |
Dexchlorpheniramine maleate;
d-Chlorpheniramine maleate
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| Formula |
C16H19ClN2. C4H4O4
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| Exact mass |
390.1346
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| Mol weight |
390.8606
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| Structure |
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| Remark |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AB Substituted alkylamines
R06AB02 Dexchlorpheniramine
D00668 Dexchlorpheniramine maleate (USP) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
44 Allergic agents
441 Antihistamines
4419 Others
D00668 Dexchlorpheniramine maleate (USP); d-Chlorpheniramine maleate (JP18)
Classification of Japanese OTC drugs [BR:br08313]
Agents for nervous and sensory systems
01 Cold remedy (oral use)
D00668 Dexchlorpheniramine maleate (USP)
06 Antivertigo drugs (incl. motion/morning sickness remedies)
D00668 Dexchlorpheniramine maleate (USP)
Allergic agents
52 Antihistamine based drugs
D00668 Dexchlorpheniramine maleate (USP)
Agents for otolaryngologic use
69 Oral medicine for nasal inflammation
D00668 Dexchlorpheniramine maleate (USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Chlorphenamine
D00668 Dexchlorpheniramine maleate (USP)
Third-class OTC drugs
Inorganic and organic chemicals
Chlorphenamine
D00668 Dexchlorpheniramine maleate (USP)
Animal drugs in Japan [BR:br08331]
96 Agents affecting metabolism
968 Antiallergic agents (including nonspecific antigen preparations)
9682 Chlorpheniramine, derivatives and preparations
C07783 Dexchlorpheniramine maleate
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01098 Dexchlorpheniramine
D00668 Dexchlorpheniramine maleate
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG01098 Dexchlorpheniramine
D00668 Dexchlorpheniramine maleate
DG01633 CYP3A/CYP3A4 substrate
DG01098 Dexchlorpheniramine
D00668 Dexchlorpheniramine maleate
Metabolizing enzyme inhibitor
DG01645 CYP2D6 inhibitor
DG01098 Dexchlorpheniramine
D00668 Dexchlorpheniramine maleate
Drug classes [BR:br08332]
Anti-allergic agent
DG01482 Histamine receptor H1 antagonist
D00668 Dexchlorpheniramine maleate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D00668 Dexchlorpheniramine maleate (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00668 d-Chlorpheniramine maleate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00668
Rx-to-OTC switch list in the USA [br08315.html]
D00668
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 C8x C 20.5308 -17.4126
2 C8y C 20.5308 -18.8307
3 C8x C 21.7590 -19.5398
4 C8x C 22.9872 -18.8307
5 C8y C 22.9872 -17.4126
6 C8x C 21.7590 -16.7035
7 C8x C 25.4435 -18.8307
8 C8y C 25.4435 -17.4126
9 C1c C 24.2153 -16.7035
10 C8x C 26.6717 -19.5398
11 C8x C 27.8998 -18.8307
12 C8x C 27.8998 -17.4126
13 N5x N 26.6717 -16.7035
14 X Cl 19.3027 -19.5398
15 C1b C 24.2153 -15.2853
16 C1b C 25.4456 -14.5750
17 N1c N 25.4456 -13.1583
18 C1a C 26.6572 -12.4586
19 C1a C 24.2008 -12.4395
20 C6a C 33.4785 -15.9462
21 C2b C 32.8034 -14.7815
22 O6a O 32.8789 -17.1864
23 O6a O 34.8291 -15.9399
24 C2b C 31.1865 -14.7877
25 C6a C 30.5175 -15.9585
26 O6a O 29.1669 -15.9585
27 O6a O 31.1990 -17.1925
BOND 27
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 7 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 8 13 2
15 2 14 1
16 9 15 1 #Down
17 15 16 1
18 16 17 1
19 17 18 1
20 17 19 1
21 20 21 1
22 20 22 1
23 20 23 2
24 21 24 2
25 24 25 1
26 25 26 1
27 25 27 2
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