Entry
Name
2-hydroxyquinoline 8-monooxygenase;
2-oxo-1,2-dihydroquinoline 8-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating)
Reaction(IUBMB)
quinolin-2-ol + NADH + H+ + O2 = quinolin-2,8-diol + NAD+ + H2O [RN:
R05158 ]
Reaction(KEGG)
Substrate
Product
Comment
Requires iron. Quinolin-2-ol exists largely as the quinolin-2(1H)-one tautomer.
History
EC 1.14.13.61 created 1999
Reference
Authors
Rosche B, Tshisuaka B, Fetzner S, Lingens F.
Title
2-Oxo-1,2-dihydroquinoline 8-monooxygenase, a two-component enzyme system from Pseudomonas putida 86.
Journal
Other DBs
LinkDB
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