KEGG ENZYME: 2.1.1.65

ENZYME: 2.1.1.65

Entry

EC 2.1.1.65                 Enzyme

Name

licodione 2'-O-methyltransferase

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:licodione 2'-O-methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + licodione = S-adenosyl-L-homocysteine + 2'-O-methyllicodione [RN:R03623]

Reaction(KEGG)

R03623

Substrate

S-adenosyl-L-methionine [CPD:C00019];
licodione [CPD:C01592]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
2'-O-methyllicodione [CPD:C02922]

Comment

As well as licodione [1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1,3-propanedione], the 2''-hydroxy-derivative and isoliquiritigenin can act as acceptors, but more slowly.

History

EC 2.1.1.65 created 1983

Reference

Authors

Ayabe, S.-I., Yoshikawa, T., Kobayashi, M. and Furuya, T.

Title

Biosynthesis of retrochalcone, echinatin: involvement of O-methyltransferase to licodione.

Journal

Phytochemistry 19:2331-2336 (1980)

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.65

IUBMB Enzyme Nomenclature:

2.1.1.65

ExPASy - ENZYME nomenclature database:

2.1.1.65

BRENDA, the Enzyme Database:

2.1.1.65

CAS:	77000-07-8

LinkDB

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