Entry
Name
4-acetamidobutyryl-CoA deacetylase;
aminobutyryl-CoA thiolesterase;
deacetylase-thiolesterase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
4-acetamidobutanoyl-CoA amidohydrolase
Reaction(IUBMB)
4-acetamidobutanoyl-CoA + H2O = acetate + 4-aminobutanoyl-CoA [RN:
R04056 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme also hydrolyses 4-aminobutanoyl-CoA to aminobutanoate and coenzyme A.
History
EC 3.5.1.51 created 1984
Reference
Authors
Ohsugi M, Kahn J, Hensley C, Chew S, Barker HA.
Title
Metabolism of L-beta-lysine by a Pseudomonas. Purification and properties of a deacetylase-thiolesterase utilizing 4-acetamidobutyryl CoA and related compounds.
Journal
J Biol Chem 256:7642-51 (1981)
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.51
ExPASy - ENZYME nomenclature database: 3.5.1.51
LinkDB
All DBs