Entry
Name
aconitate Delta-isomerase;
aconitate isomerase
Class
Isomerases;
Intramolecular oxidoreductases;
Transposing C=C bonds
BRITE hierarchy
Sysname
aconitate Delta2-Delta3-isomerase
Reaction(IUBMB)
trans-aconitate = cis-aconitate [RN:
R02244 ]
Reaction(KEGG)
Substrate
Product
Comment
cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. This isomerization could take place either in a direct cis-trans interconversion or by an allylic rearrangement; the enzyme has been shown to catalyse the latter change.
History
EC 5.3.3.7 created 1972
Pathway
ec00660 C5-Branched dibasic acid metabolism
Orthology
K22002 aconitate Delta-isomerase
K22003 aconitate Delta-isomerase
Genes
PPAO : K3169_06385 K3169_25970
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Taxonomy
Reference
Authors
Klinman JP, Rose IA.
Title
Purification and kinetic properties of aconitate isomerase from Pseudomonas putida.
Journal
Reference
Authors
Klinman JP, Rose IA.
Title
Mechanism of the aconitate isomerase reaction.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 5.3.3.7
ExPASy - ENZYME nomenclature database: 5.3.3.7
BRENDA, the Enzyme Database: 5.3.3.7
LinkDB
All DBs