Entry |
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Name |
8-oxocoformycin reductase;
8-ketodeoxycoformycin reductase
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
coformycin:NADP+ 8-oxidoreductase
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Reaction(IUBMB) |
coformycin + NADP+ = 8-oxocoformycin + NADPH + H+ [RN: R03667]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Si-specific with respect to NADPH. Also reduces 8-oxodeoxy-coformycin to the nucleoside antibiotic deoxycoformycin.
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History |
EC 1.1.1.235 created 1992
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Reference |
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Authors |
Hanvey JC, Hawkins ES, Baker DC, Suhadolnik RJ. |
Title |
8-Ketodeoxycoformycin and 8-ketocoformycin as intermediates in the biosynthesis of 2'-deoxycoformycin and coformycin. |
Journal |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.235 |
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LinkDB |
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