Entry |
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Name |
galactitol-1-phosphate 5-dehydrogenase;
gatD (gene name)
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
galactitol-1-phosphate:NAD+ oxidoreductase
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Reaction(IUBMB) |
galactitol 1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+ [RN: R05571]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
The enzyme from the bacterium Escherichia coli is involved in a galactitol degradation pathway. It contains two zinc atoms per subunit.
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History |
EC 1.1.1.251 created 1999
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Pathway |
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Orthology |
K00094 | galactitol-1-phosphate 5-dehydrogenase |
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Genes |
ECOO: | ECRM13514_2806(gatD) |
ECOH: | ECRM13516_2720(gatD) |
ECW: | EcE24377A_2379(gatD) |
EDJ: | ECDH1ME8569_2025(gatD) |
ECOI: | ECOPMV1_02249(tdh_3) |
KIE: | NCTC12125_04489(gutB_2) |
AHN: | NCTC12129_03669(gatD_2) |
PHEI: | NCTC12003_03174(tdh_2) |
» show all
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Reference |
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Authors |
WOLFF JB, KAPLAN NO |
Title |
Hexitol metabolism in Escherichia coli. |
Journal |
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Reference |
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Authors |
Nobelmann B, Lengeler JW |
Title |
Sequence of the gat operon for galactitol utilization from a wild-type strain EC3132 of Escherichia coli. |
Journal |
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Sequence |
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Reference |
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Authors |
Benavente R, Esteban-Torres M, Kohring GW, Cortes-Cabrera A, Sanchez-Murcia PA, Gago F, Acebron I, de las Rivas B, Munoz R, Mancheno JM |
Title |
Enantioselective oxidation of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase from Escherichia coli. |
Journal |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.251 |
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LinkDB |
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