The biosynthesis of raucaffrinoline from perakine is a side route of the ajmaline biosynthesis pathway. The enzyme is a member of the aldo-keto reductase enzyme superfamily from higher plants.
Sun L, Ruppert M, Sheludko Y, Warzecha H, Zhao Y, Stockigt J
Title
Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia.
Rosenthal C, Mueller U, Panjikar S, Sun L, Ruppert M, Zhao Y, Stockigt J
Title
Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants.