KEGG   ENZYME: 1.1.1.326
Entry
EC 1.1.1.326                Enzyme                                 
Name
zerumbone synthase;
ZSD1
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
10-hydroxy-alpha-humulene:NAD+ oxidoreductase
Reaction(IUBMB)
10-hydroxy-alpha-humulene + NAD+ = zerumbone + NADH + H+ [RN:R09988]
Reaction(KEGG)
R09988
Substrate
10-hydroxy-alpha-humulene [CPD:C20229];
NAD+ [CPD:C00003]
Product
zerumbone [CPD:C20262];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme was cloned from shampoo ginger, Zingiber zerumbet.
History
EC 1.1.1.326 created 2012
Orthology
K21837  zerumbone synthase
Reference
1  [PMID:21668645]
  Authors
Okamoto S, Yu F, Harada H, Okajima T, Hattan J, Misawa N, Utsumi R
  Title
A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet.
  Journal
FEBS J 278:2892-900 (2011)
DOI:10.1111/j.1742-4658.2011.08211.x
  Sequence
[ag:BAK09296]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.326
IUBMB Enzyme Nomenclature: 1.1.1.326
ExPASy - ENZYME nomenclature database: 1.1.1.326
BRENDA, the Enzyme Database: 1.1.1.326
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