Entry
Name
2-alkyl-3-oxoalkanoate reductase;
oleD (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(2R,3S)-2-alkyl-3-hydroxyalkanoate:NADP+ oxidoreductase
Reaction(IUBMB)
a (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP+ = an (R)-2-alkyl-3-oxoalkanoate + NADPH + H+ [RN:
R11774 ]
Reaction(KEGG)
Substrate
(2R,3S)-2-alkyl-3-hydroxyalkanoate [CPD:
C21645 ];
NADP+ [CPD:
C00006 ]
Product
Comment
The enzyme, found in certain bacterial species, is part of a pathway for the production of olefins.
History
EC 1.1.1.412 created 2017
Orthology
K22320 2-alkyl-3-oxoalkanoate reductase
Genes
XPH : XppCFBP6546_10725(XppCFBP6546P_10725)
XHD : LMG31886_02600(oleD_1)
LLZ : LYB30171_00153(oleD)
SCAA : TUM17387_25550(oleD)
SAMY : DB32_000492 DB32_004413
NSR : NS506_01609 NS506_05576
NTP : CRH09_11575 CRH09_29065
NOD : FOH10_01635 FOH10_07000
NAD : NCTC11293_03165 NCTC11293_05892
NTC : KHQ06_10835 KHQ06_28985
NHU : H0264_10040 H0264_35195
NAQU : ENKNEFLB_01766(oleD_1)
» show all
Taxonomy
Reference
Authors
Bonnett SA, Papireddy K, Higgins S, del Cardayre S, Reynolds KA
Title
Functional characterization of an NADPH dependent 2-alkyl-3-ketoalkanoic acid reductase involved in olefin biosynthesis in Stenotrophomonas maltophilia.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.412
LinkDB
All DBs