KEGG   ENZYME: 1.1.1.425
Entry
EC 1.1.1.425                Enzyme                                 
Name
levoglucosan dehydrogenase;
1,6-anhydro-beta-D-glucose dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
1,6-anhydro-beta-D-glucopyranose:NAD+ 3-oxidoreductase
Reaction(IUBMB)
levoglucosan + NAD+ = 3-dehydrolevoglucosan + NADH + H+ [RN:R12713]
Reaction(KEGG)
R12713
Substrate
levoglucosan [CPD:C22350];
NAD+ [CPD:C00003]
Product
3-dehydrolevoglucosan [CPD:C22351];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Levoglucosan is formed from the pyrolysis of carbohydrates such as starch and cellulose and is an important molecular marker for pollution from biomass burning. This enzyme is present only in bacteria, and has been characterized from Arthrobacter sp. I-552 and Pseudarthrobacter phenanthrenivorans. cf. EC 2.7.1.232, levoglucosan kinase.
History
EC 1.1.1.425 created 2021
Orthology
K24995  levoglucosan dehydrogenase
Genes
RFO: REIFOR_02758(iolG)
SMI: BN406_06768
RHI: NGR_b19940
SFD: USDA257_c18000
SAME: SAMCFNEI73_pC1598
REL: REMIM1_PF00849
REP: IE4803_CH03661
RLT: Rleg2_4779
RGR: FZ934_12315
PHL: KKY_2595 KKY_3864
DEI: C4375_04075
PZH: CX676_22085
PTP: RCA23_c12140
LVS: LOKVESSMR4R_02604(iolX)
FAQ: G5B39_17710
BACQ: DOE78_19795
BCO: Bcell_0373 Bcell_0375
BMQ: BMQ_1775
BMD: BMD_3622
BMEG: BG04_545
BFX: BC359_10195
BKW: BkAM31D_16255(gfo_2)
SALE: EPH95_12700
NTM: BTDUT50_05740
MEKU: HUW50_14340
SHV: AAT16_11375 AAT16_11385
PPY: PPE_00856
POW: IJ21_32400 IJ21_33360
COH: EAV92_02890
JEO: JMA_08640 JMA_08660
EAV: EH197_20100
LUA: D4A81_10270
CMIU: B1H56_01165
TEX: Teth514_0988
THX: Thet_1927
MLV: CVS47_02172(afr_3)
MSF: IT882_02490
RLA: Rhola_00001010
ART: Arth_1911
ARTH: C3B78_05130
PUE: FV140_21400
APN: Asphe3_10730
KFV: AS188_10240
SATK: SA2016_1510
TEZ: BKM78_07725
TLA: TLA_TLA_01561(iolX_2)
DGO: DGo_PB0088
 » show all
Reference
1  [PMID:7765713]
  Authors
Nakahara K, Kitamura Y, Yamagishi Y, Shoun H, Yasui T.
  Title
Levoglucosan dehydrogenase involved in the assimilation of levoglucosan in Arthrobacter sp. I-552.
  Journal
Biosci Biotechnol Biochem 58:2193-6 (1994)
DOI:10.1271/bbb.58.2193
Reference
2  [PMID:30224354]
  Authors
Sugiura M, Nakahara M, Yamada C, Arakawa T, Kitaoka M, Fushinobu S.
  Title
Identification, functional characterization, and crystal structure determination of bacterial levoglucosan dehydrogenase.
  Journal
J Biol Chem 293:17375-17386 (2018)
DOI:10.1074/jbc.RA118.004963
  Sequence
[apn:Asphe3_10730]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.425
IUBMB Enzyme Nomenclature: 1.1.1.425
ExPASy - ENZYME nomenclature database: 1.1.1.425
BRENDA, the Enzyme Database: 1.1.1.425
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