Other purine and pyrimidine nucleosides (as well as 2'-deoxyribonucleosides) are substrates, but ribose and nucleotides are not substrates. The overall reaction takes place in two separate steps, with the 5'-dehydro nucleoside being released from the enzyme to serve as substrate for the second reaction. This enzyme differs from EC 1.1.3.39, nucleoside oxidase (H2O2-forming), as it produces water rather than hydrogen peroxide.
History
EC 1.1.3.28 created 1992, modified 2001
Reference
1
Authors
Isono, Y., Sudo, T. and Hoshino, M.
Title
Purification and reaction of a new enzyme, nucleoside oxidase.
Journal
Agric Biol Chem 53:1663-1669 (1989)
Reference
2
Authors
Isono, Y., Sudo, T. and Hoshino, M.
Title
Properties of a new enzyme, nucleoside oxidase, from Pseudomonas maltophilia LB-86.