| Entry |
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| Name |
1-hydroxy-2-naphthoate 1,2-dioxygenase;
1-hydroxy-2-naphthoate dioxygenase;
1-hydroxy-2-naphthoate-degrading enzyme;
1-hydroxy-2-naphthoic acid dioxygenase;
1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)
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| Class |
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
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| Sysname |
1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (ring-opening)
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| Reaction(IUBMB) |
1-hydroxy-2-naphthoate + O2 = (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate [RN: R07657]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate [CPD: C16149]
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| Comment |
Requires Fe2+. Involved, with EC 4.1.2.34 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase, in the metabolism of phenanthrene in bacteria.
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| History |
EC 1.13.11.38 created 1989
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| Pathway |
| ec00624 | Polycyclic aromatic hydrocarbon degradation |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K11948 | 1-hydroxy-2-naphthoate dioxygenase |
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| Genes |
| MMON: | EWR22_08305 EWR22_21570 |
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| Reference |
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| Authors |
Barnsley EA. |
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| Title |
Phthalate pathway of phenanthrene metabolism: formation of 2'-carboxybenzalpyruvate. |
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| Journal |
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| Other DBs |
| UM-BBD (Biocatalysis/Biodegradation Database): | 1.13.11.38 |
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| LinkDB |
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