KEGG   ENZYME: 1.3.1.6
Entry
EC 1.3.1.6                  Enzyme                                 
Name
fumarate reductase (NADH);
NADH-fumarate reductase;
NADH-dependent fumarate reductase;
fumarate reductase (NADH)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
succinate:NAD+ oxidoreductase
Reaction(IUBMB)
succinate + NAD+ = fumarate + NADH + H+ [RN:R00402]
Reaction(KEGG)
R00402
Substrate
succinate [CPD:C00042];
NAD+ [CPD:C00003]
Product
fumarate [CPD:C00122];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.3.1.6 created 1972
Pathway
ec00720  Other carbon fixation pathways
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01120  Microbial metabolism in diverse environments
Orthology
K18556  NADH-dependent fumarate reductase subunit A
K18557  NADH-dependent fumarate reductase subunit B
K28482  fumarate reductase (NADH)
Genes
ENC: ECL_03250
ENL: A3UG_14535
ECLG: EC036_28130
ECLE: ECNIH2_14770
ECLN: ECNIH4_08390
ECLI: ECNIH5_13690
ECLX: LI66_14210
ECLY: LI62_15555
ECLZ: LI64_13620
ECLO: ENC_41960
EHM: AB284_11285
EXF: BFV63_13955
ECLA: ECNIH3_13745
ECLC: ECR091_13680
EAU: DI57_04975
EKB: BFV64_14355
ENO: ECENHK_14230
EEC: EcWSU1_02908(fccA)
ELG: BH714_10320
ECAN: CWI88_08235
ERN: BFV67_13865
ECLS: LI67_011645
ECHG: FY206_15770
ESH: C1N69_14345
EPT: HWQ17_21610
ENT: Ent638_2558
EAS: Entas_2764
ENR: H650_01005
ENX: NI40_014225
ENF: AKI40_3457
LNI: CWR52_20845
EBG: FAI37_14955
END: A4308_18930
ENZ: G0034_14830
ENS: HWQ15_22420
ENK: LOC22_02200
EHU: D5067_0008730
EMOR: L6Y89_13590
ENB: ELK40_14550
EQU: OM418_13935
EPU: QVH39_14890
EDY: F0320_13725
EAX: AAHF05_13850
ENTL: FZF21_18785
ENTC: NWV12_14100
ENTJ: RY075_14675
KPN: KPN_01548
KPU: KP1_2565
KPH: KPNIH24_15965
KPZ: KPNIH27_11950
KPV: KPNIH29_12455
KPW: KPNIH30_12740
KPY: KPNIH31_11825
KPG: KPNIH32_12580
KPC: KPNIH10_12265
KPQ: KPR0928_12270
KPT: VK055_0954
KPO: KPN2242_10530
KPR: KPR_2762
KPJ: N559_2777
KPI: D364_07850
KPA: KPNJ1_02931
KPS: KPNJ2_02931
KPX: PMK1_03867(fccA)
KPB: FH42_03645
KPNE: KU54_013920
KPNU: LI86_13855
KPNK: BN49_2657
KVA: Kvar_2810
KPE: KPK_2907
KPK: A593_22295
KVD: KR75_20115
KVQ: SP68_01150
KQU: AVR78_16855
KQV: B8P98_14750
KOX: KOX_21720
KOE: A225_3217
KOY: J415_15865
KOM: HR38_20020
KMI: VW41_04410
KOK: KONIH1_15770
KOC: AB185_20130
EAE: EAE_18220
EAR: CCG30247
KLL: BJF97_15890
KLW: DA718_13325
KAR: LGL98_13475
KGR: JJJ10_12940
KPAS: LUW96_22475
KLC: K7H21_12790
KLM: BWI76_16100
REE: electrica_02340(fccA)
KLP: GUC22_11810
KLX: GQR96_11220
ROR: RORB6_05405
RON: TE10_15840
RPLN: B1209_12070
RAO: DSD31_11880
EBT: EBL_c34160(fccA)
CNT: JT31_07885
CEM: LH23_09825
CEN: LH86_09895
CLAP: NCTC11466_03607(fccA)
PGE: LG71_22235
ESC: Entcl_1690
KLE: AO703_13520
KSA: C813_01650
KOR: AWR26_10920
KRD: A3780_13200
KCO: BWI95_18205
KOT: EH164_10025
KPSE: IP581_12970
KOB: HF650_12880
KOO: O9K67_10925
KOU: C0557_14250
KCA: AAEY27_10080
KIE: NCTC12125_00701(fccA)
KAS: KATP_16500
KLU: K7B04_20285
KCY: RIN60_08555
KGN: GY169_08815
LEF: LJPFL01_2607
LEW: DAI21_13115
BFT: MNO13_03860
BSEL: RHD99_00615
YRE: HEC60_00070
SGOE: A8O29_016810
KIN: AB182_14430
PDZ: HHA33_17065
METY: MRY16398_32630
IZH: FEM41_08625
PSGC: G163CM_06750(namA_1)
MPHG: MPHASIOC01_004289
EBF: D782_1666
EBC: C2U52_25025
EBU: CUC76_03255
RAH: Rahaq_2310 Rahaq_5031
RACE: JHW33_05300 JHW33_24420
RAQ: Rahaq2_2415 Rahaq2_4906
RAA: Q7S_11695 Q7S_25351
ROX: BV494_05305 BV494_22190
RVC: J9880_18755 J9880_21855
RBON: QNM34_10680 QNM34_11945
RIU: I2123_06925 I2123_13235
GQU: AWC35_15065
EAME: GXP68_03155 GXP68_16785
ECA: ECA1969
PATR: EV46_09465
PATO: GZ59_26300
PCC: PCC21_024500
PCV: BCS7_11830
PWA: Pecwa_2625
PPAR: A8F97_05555
PEC: W5S_2596
PWS: A7983_20495
PPOA: BJK05_06585
PBRA: B5S52_10055
PPUJ: E2566_12150
PARI: I2D83_12580
PAQU: DMB82_0009840
PVZ: OA04_19150
PPAV: LOZ86_11805
PQU: IG609_011085
PPOO: LW347_11860
PACB: M9782_14285
PARL: PEC302110_22460
PPEU: DUT67_09380
DZE: Dd1591_3495
DDC: Dd586_0570
DZC: W909_02930
DSO: A4U42_12100
CED: LH89_09305
DFN: CVE23_03430
DDQ: DDI_0374
DAQ: DAQ1742_00629
DIC: Dpoa569_0003382
DLC: O1Q98_08730
DAD: V6C41_11130
DDA: Dd703_3126
BGJ: AWC36_18675
BRB: EH207_08070
BNG: EH206_09060
BIZ: HC231_23680
LBQ: CKQ53_17280
LPOP: I6N93_11445
EAM: EAMY_1562(frdC)
EAY: EAM_1539
ETA: ETA_19260
EPY: EpC_20150
EPR: EPYR_02170(frdC)
EBI: EbC_17380
ERJ: EJP617_27100
EPE: CI789_09695
ERWI: GN242_08560
ETP: LU633_10705
ERP: LJN55_09875
EPI: Q3V30_08560
ERWE: GKQ23_10210
ETO: RIN69_06465
EGE: EM595_p0146
PAM: PANA_4117(yqiG)
PLF: PANA5342_p10276
PAJ: PAJ_p0173(yqiG)
PAQ: PAGR_p204
PVA: Pvag_pPag30231
PAGG: AL522_02270
PAO: Pat9b_1582
KLN: LH22_14410
PANT: PSNIH1_12205
PAGC: BEE12_20075
PSTW: DSJ_26070
PANS: FCN45_08010
PEY: EE896_20685
PDIS: D8B20_07270
PER: LAC65_06440
PJI: KTJ90_20675
PANO: OJ965_01705
KPIE: N5580_10250
PALF: K6R05_21170
PPHO: CTZ24_08430
PDIP: KFZ74_12030
PANE: P6287_08010
PAMT: IAI47_20425
PANZ: NR302_08065
PALT: ACRPH8_22555
TCI: A7K98_02185
TPTY: NCTC11468_00478(ifcA)
TATU: EFZ10_02020
PMAK: PMPD1_1268
HBH: E4T21_02005
TAU: Tola_2554
GAP: GAPWK_1458
GAQ: RAM11_07150
SALV: SALWKB2_0870
SCOM: PYG29_05415
TRB: HB776_21850
SSEI: FJR45_00205
SBAL: HUE88_00200
SMAS: HUE87_00215
SMAX: FJR03_00200
SAQT: GJV85_00315
SDIZ: WCY31_00585
TZH: WCX18_07445
TSUL: LOH54_07570
TSUB: WCX49_07640
TIMM: WCX72_00590 WCX72_07355
HMZ: WCX87_00205 WCX87_07520
HSJ: WCY03_00210 WCY03_07765
SJI: WCY20_00520 WCY20_13055
SULU: SFB89_05130
AELL: AELL_0101(sdhA)
AVP: AVENP_0118(sdhA)
ADZ: ADFLV_0132(sdhA)
AROS: NJU99_00470
AIE: LXN10_07340
ALK: ALEK_0095(sdhA)
HBV: ABIV_0055(sdhA)
HEBR: AEBR_0166(sdhA)
HTM: RZR91_01205
HCJ: HCR_14220(frdA_2)
SMAB: LN246_00910
NIH: NitYY0810_C0006
AAE: aq_553(frdB1) aq_594(frdA)
HYA: HY04AAS1_0305 HY04AAS1_0635
HHO: HydHO_0304 HydHO_0624
HYS: HydSN_0315 HydSN_0638
HTH: HTH_0983(frdB) HTH_1421(frdA)
HTE: Hydth_0979 Hydth_1410
TAL: Thal_0289 Thal_1165
TRD: THERU_04095 THERU_07395
PDIZ: IAE16_06165 IAE16_06930
PFLO: G3M65_05770 G3M65_06390
SUL: SYO3AOP1_0248
SAF: SULAZ_0178(sdhA)
PMX: PERMA_1387(sdhA)
TAM: Theam_1273
DTE: Dester_0445
NCD: ACONDI_03104(frdA_3)
MEME: HYG87_08475
MEER: NKF70_09425
 » show all
Reference
1
  Authors
Hopgood MF, Walker DJ.
  Title
Succinic acid production by rumen bacteria. III. Enzymic studies on the formation of succinate by Ruminococcus flavefaciens.
  Journal
Aust J Biol Sci 22:1413-1424 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.6
IUBMB Enzyme Nomenclature: 1.3.1.6
ExPASy - ENZYME nomenclature database: 1.3.1.6
BRENDA, the Enzyme Database: 1.3.1.6
CAS: 9076-99-7
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