KEGG   ENZYME: 1.3.1.65
Entry
EC 1.3.1.65                 Enzyme                                 
Name
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase
Reaction(IUBMB)
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+ = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H+ [RN:R05312]
Reaction(KEGG)
R05312
Substrate
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline [CPD:C06726];
NAD+ [CPD:C00003]
Product
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline [CPD:C06725];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts in the reverse direction to form part of the 3-methylquinoline degradation pathway in bacteria.
History
EC 1.3.1.65 created 2000
Reference
1  [PMID:8489738]
  Authors
Schach S, Schwarz G, Fetzner S, Lingens F.
  Title
Microbial metabolism of quinoline and related compounds. XVII. Degradation of 3-methylquinoline by Comamonas testosteroni 63.
  Journal
Biol Chem Hoppe Seyler 374:175-81 (1993)
DOI:10.1515/bchm3.1993.374.1-6.175
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.65
IUBMB Enzyme Nomenclature: 1.3.1.65
ExPASy - ENZYME nomenclature database: 1.3.1.65
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.65
BRENDA, the Enzyme Database: 1.3.1.65
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