KEGG ENZYME: 1.4.1.17

ENZYME: 1.4.1.17

Entry

EC 1.4.1.17                 Enzyme

Name

N-methylalanine dehydrogenase

Class

Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor

Sysname

N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating)

Reaction(IUBMB)

N-methyl-L-alanine + H2O + NADP+ = pyruvate + methylamine + NADPH + H+ [RN:R01584]

Reaction(KEGG)

Substrate

N-methyl-L-alanine [CPD:C02721];
H2O [CPD:C00001];
NADP+ [CPD:C00006]

Product

pyruvate [CPD:C00022];
methylamine [CPD:C00218];
NADPH [CPD:C00005];
H+ [CPD:C00080]

History

EC 1.4.1.17 created 1984

Reference

1 [PMID:236301]

Authors

Lin MC, Wagner C.

Title

Purification and characterization of N-methylalanine dehydrogenase.

Journal

J Biol Chem 250:3746-51 (1975)

Other DBs

ExplorEnz - The Enzyme Database:

IUBMB Enzyme Nomenclature:

ExPASy - ENZYME nomenclature database:

BRENDA, the Enzyme Database:

CAS:	56379-51-2

LinkDB

DBGET integrated database retrieval system